Stem Cells - Epidermolysis Bullosa Treatment With Stem Cells
Monday, April 29, 2019
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| Stem Cells |
Healthy-best.blogspot.com- The Sense Of Epidermolysis Buallosa - Epidermolysis bullosa (EB) is a combination of a variety of conditions related to the derivative of a rare connective tissue disorder that caused a form of skin and mucous membrane blisters.
Skin blister on the outside as well as in the body is the reaction of friction when rubbing, scratching, exposed to heat, or minor injury. This condition generally develops in infants and young children, and can also appear in adolescence or adult teen.
Epidermolysis bullosa (EB) is a derivative of the disease consists of a variety of classification depends on the location of the layer of skin that blisters, among others on the outermost layer (the epidermis), the lower layer (dermis), or basal membrane area. The basal membrane area is the area between the epidermis and the dermis.
Prevention Epidermolysis Bulosa
Precautions can be made to epidermolysis disease bullosa is to prevent the emergence of skin blisters and infection. These are some steps that you can do:
• The infant or child in need of attention to his parents to get comfortable while being sick. Carry it a child with as soft as possible and make sure to place it on top of objects covered with a soft material.
Do not lift children from under her arm. Carrying a child by using your hands to support part of the buttocks and his neck.
• Set the temperature inside your home to keep it cool. In addition, keep his skin moist by applying Moisturiser, such as petroleum jelly.
• Wear clothing that is made from soft and easy to be removed and worn again. You can use the specially made shoes that are soft or padded cushioning at sewing children's clothing in the area of the elbows, knees, and other areas that have the pressure points of the body.
• Remove the elastic rubber that is attached to a disposable diaper, then lightly coat the inside with a bandage from sticking, or sprinkle with a paste containing zinc oxide (zinc oxide) before use.
• Avoid scratching the blisters by making sure the nails short or wear gloves on the baby before she sleeps to prevent wound infections due to scratching.
• Avoid hard objects and surfaces with a coating of seats using a soft material. Use an air mattress, sheets, and blankets for the bed's soft child sufferers of EB.
• Restrict children from physical activity that might cause the skin to ease string, scratched, or hurt. You can start by wearing pants or a long shirt on the child who wanted to play outdoors.
• Make sure you or medical personnel do not use bandages adhesive strong on the skin to prevent skin blisters rupture and could result in the loss of fluid and the onset of the infection.
As supporting measures, provide food and to support the development and growth of the child, as well as help the healing of his wounds.
Taking vitamins and supplements can also help prevent the development of complications. Preferred administering nutrients calcium, iron, and vitamin D.
Treatment Of Epidermolysis Bulosa
Drugs to tackle epidermolysis bulosa has not been found, but in some cases, the condition the sufferer can be improved along with the increase of age.
The treatment is done to treat symptoms, preventing pain and wounds, especially in the more serious cases and the risk of occurrence of fatal complications to death.
A team that included doctors, nurses, and healthcare professionals from diverse specializations will be involved in the treatment process epidermolysis bulosa (EB). The EB treatment alone has some handling steps that can be undertaken, namely:
• Administering medication to control the itching and pain and prevent complications. The tablets drink antibiotics is one of the types of drugs that will be given if the sufferers showed symptoms of infection, such as fever and lymph nodes that swell.
Another drink tablets may be given the antifading drug is a corticosteroid to reduce pain due to difficulty swallowing.
• Operating procedures may be done to improve the function of the organs is compromised due to this condition or improve the ability of the body consumes foods that are healthy and balanced.
Operating procedure consists of:
The narrowing of the esophagus dilates the esophagus – caused by the appearance of blisters and scarring can make sufferers feel difficulty eating.
Treatment through the operations carried out to facilitate food goes into the stomach and can digest the body. The operation is done by means of inserting a balloon into the esophagus, and then developed/blown to widen the area.
To restore the ability of motion (mobility) organs – Blisters and scarring that constantly appears will trigger changes in the form of the joint organs, for example, the RADIUS that blends or bent so that interfere with normal movement.
Gastrostomy – Installation Tube is a tube inserted gastronomy from the outer wall of the stomach directly into the stomach.
This tube is aimed at helping the body get the nutrients it needs intake when the patient swallows hard and help weight gain recommended the doctor. Sufferers can still continue to eat by using their mouths if it is possible.
Transplant skin – Most sufferers require this procedure to treat injuries resulting from EB.
• Rehabilitation therapy can help sufferers recover his body movement limited or interrupted due to the appearance of scarring or skin retracts because of epidermolysis bulosa.
One of the therapies used is swimming to maintain the mobility of the body. This therapy will also help sufferers do everyday activities safely and comfortably.
There are also procedures to other EB treatment are still examined by experts, such as gene therapy, bone marrow transplantation, the replacement proteins, and cell-based therapies.
Ask your doctor about the development of the procedure the current treatment that can be used to treat epidermolysis bulosa.
Caring for EB sufferers at home requires adequate knowledge of these diseases and how to deal with skin blisters or sores that appear.
Blisters that are left can be widened and creating a larger wound when it broke. Consult the doctor in figuring out how to crack and dry out the blisters in order not to widen as well as products that can be used to heal, damming, and prevent infection.
Here are some steps to take care and wrap the wound or exposed skin EB:
• The child or adult can consume the medicine the doctor prescribed pain reliever about 30 minutes before the bandage was done. Sufferers who do not respond to pain relief drugs can use drugs anti-seizure. Consult a physician before using these medicines.
• Wash your hands before touching blisters or replace the gauze bandage the wound.
• Soak the bandage area too stick to the wound into the warm water and wait until detached itself or loose. Do not pull the bandage by force as this may break the blisters.
• Clean the wound by means of soaking in a solution of water and salt for 5-10 minutes, afterward rinse with warm water or lukewarm. Another solution is to use a solution of vinegar mixed with bleach. This helps reduce the pain that may appear when the bandage.
• As a safety step, wrap your hands and feet which blister each day to prevent changing the shape of organs or finger is attached to.
• Use a sterile needle to break the newly formed blisters to prevent it from spreading. Do not peel the skin that remains, let it dry out a will while protecting the skin layer underneath.
• Use a cream or lotion before you wrap the wound with a bandage. Some type of cream that can be used is the antibiotic cream, petroleum jelly, or other humidifiers.
Change the type of antibiotic cream used for too long with other types of each month. Please choose the appropriate bandages with the needs, abilities, and the condition of the wound.
Handle blisters that appear inside the cavity of the mouth or throat in people with children at home will require patience and perseverance because children still need the intake of nutrients derived from food.
Here are some ways that you can do:
• Apply the gel in the mouth pain reliever infants blister due to the milk or the milk bottle. You could try using a dot that is specifically made for premature babies, a syringe, or a medicine dropper end made of rubber for breastfeeding the child.
• Serve food nutritious vegetables that are soft and easily swallowed, such as vegetable soup, fruit juice, processed solids and mixed with milk or broth (puree).
• Serve food and drinks in warm temperatures, the same as room temperature, or cold.
It is advisable to consult a doctor before deciding whether it is worth giving supplements to children or whether children need other treatment measures.
References:
Coulombe, PA. et al. (2009). Epidermolysis Bullosa Simplex: A Paradigm for Disorder of Tissue
Fragility. The Journal of Clinical Investigation, 119 (7), pp. 1784-1793 Sawamura, d. et al. (2010).
Overview of Epidermolysis Bullosa. Japanese Dermatological Association, 37 (3), pp. 214-219 NIH
(2018). Genetics Home Reference. Dystrophic Epidermolysis Bullosa.
NHS Choices UK (2018). Health A-Z. Epidermolysis Bullosa.
Mayo Clinic (2018). Diseases and Conditions. Epidermolysis Bullosa.
KidsHealth (2018). Gastrostomy Tube (G-Tube).
Kinman, et al. Healthline (2018). Milium Cysts in Adults and Babies.
Knott, b. Patient (2016). Epidermolysis Bullosa.
Coulombe, PA. et al. (2009). Epidermolysis Bullosa Simplex: A Paradigm for Disorder of Tissue
Fragility. The Journal of Clinical Investigation, 119 (7), pp. 1784-1793 Sawamura, d. et al. (2010).
Overview of Epidermolysis Bullosa. Japanese Dermatological Association, 37 (3), pp. 214-219 NIH
(2018). Genetics Home Reference. Dystrophic Epidermolysis Bullosa.
NHS Choices UK (2018). Health A-Z. Epidermolysis Bullosa.
Mayo Clinic (2018). Diseases and Conditions. Epidermolysis Bullosa.
KidsHealth (2018). Gastrostomy Tube (G-Tube).
Kinman, et al. Healthline (2018). Milium Cysts in Adults and Babies.
Knott, b. Patient (2016). Epidermolysis Bullosa.