Acanthosis Nigricans - Symptoms and Causes of Acanthosis Nigricans

Acanthosis Nigricans - Symptoms and Causes of Acanthosis Nigricans

Healthy-best.blogspot.com-  Acanthosis Nigricans is a disorder of pigmentation of the skin which is not contagious and usually does no harm. However, this condition can be a sign of mild to severe health problems.

Acanthosis nigricans marked the folds of blackened skin, thickened, and textured like velvet fabric. This leaves the skin area odor and itching on the skin.

The Cause Of The Akantosis Nigrikans

Not yet known for certain the cause of acanthosis nigricans, but generally these conditions associated with insulin resistance.

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Following a number of causes of acanthosis nigricans:

• Obesity. Acanthosis nigricans usually appear due and obesity. The more weight, the higher the risk of suffering from acanthosis nigricans.

• Insulin resistance. This condition causes the body cannot use insulin properly. Insulin is a hormone produced in the pancreas to control blood sugar levels. Insulin resistance is the cause of the disease of type 2 diabetes and most people with acanthosis nigricans also have insulin resistance.

• The use of drugs and supplements. Acanthosis nigricans can be caused by the use of drugs and supplements as medication oral contraceptives (birth control pills), a corticosteroid such as prednisone, and niacin in high doses.

• Hormonal Disorders. Acanthosis nigricans can occur in people with hormone disorders such as hypothyroidism (underactive thyroid gland), ovarian cyst sufferers, and in patients with reduced production of hormones in the adrenal glands (Addison's disease)

• Cancer. Acanthosis nigricans can occur in patients of cancer such as lymphoma or other tumors on internal organs. Generally the tumor region of the stomach, liver, and colon (colon).

• Abnormalities of the pituitary gland (pituitary) in the brain.

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Symptoms Of Akantosis Nigrikans

Symptoms of acanthosis nigricans are marked by areas of gray colored skin tanned, blackened or darker than the surrounding skin. Skin conditions in this area are dry, itchy, and a rough textured like velvet. Skin areas commonly afflicted by acanthosis nigricans is:

• Lip.
• Neck.
• Underarm.
• The palms.
• Knuckles.
• Elbow.
• Fold the thigh.
• Knee.
• The soles of the feet.

The Diagnosis Of Akantosis Nigrikans

Doctors can recognize acanthosis nigricans through observations directly to the skin of the patient. Generally, doctors are checking whether the patient has diabetes or insulin resistance, blood sugar tests or through test insulin fasting first.

In addition, the patient's medical history is also examined, including a history of consumption of vitamin and mineral supplements, or supplement-forming muscle mass.

In rare cases, the doctor will take a little piece of skin sample (biopsy) of the affected acanthosis nigricans to be examined in the laboratory. On acanthosis nigricans who is not known for sure cause, doctors recommend blood tests and a number of other tests to ascertain the cause.
 

Treatment Of Akantosis Nigrikans

Treatment acanthosis nigricans aiming to tackle the causes of the acanthosis nigricans. Doctors generally will suggest handling include:

• Weight loss.
• Drug Consumption to improve the levels of hormones in the body if acanthosis nigricans is caused by hormonal abnormalities.
• Blood sugar-lowering drugs are given when experiencing diabetes.
• Surgery, chemotherapy, or radiotherapy for patients with cancer.

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In addition to addressing its causes, to improve the appearance of the skin can be given treatment, such as:

• Skin lightening Creams containing alpha hydroxy acid, salicylic acid, and urea.
• Antibiotic Cream.
• Antibacterial Soap.
• Isotretinoin acne medication such as drinking and antibiotics.
• Laser therapy that focuses rays fired to improve the appearance of the skin.

Complications Of Akantosis Nigrikans

Complications of acanthosis nigricans are heavily dependent on the cause. Acanthosis incurred as adults need to look for to know the cause. Insulin resistance and type 2 diabetes are most often associated with acanthosis nigricans, but the possibility of cancer should not be ignored.

Prevention Of Akantosis Nigrikans

Acanthosis nigricans is not simply a skin disorder. To prevent it is to prevent the cause, among them:

• Reduce excess weight or obesity, for example by undergoing a good diet and regular exercise.

• Replace certain drugs that can trigger the onset of acanthosis nigricans. Consultation to physicians regarding the reimbursement of medicines.

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Visit a specialist doctor immediately if you experience skin changes color and form, both small and large changes. Sometimes a small change can be an early symptom of diabetes or other health problems.

References:
Kapoor, s. (2010). Diagnosis and Treatment of Acanthosis nigricans. Skinmed, 8 (3), pp. 161-164.
Phiske, MM. (2014). An Approach to Acanthosis Nigricans. IDOJ, 5 (3), pp. 239-249.
AAD (2018). Acanthosis Nigricans.
NHS Choices UK (2015). Health A-Z. Acanthosis Nigricans.
Mayo Clinic (2015). Diseases and Conditions. Acanthosis Nigricans.
American Academy of Dermatology. Diseases and Treatments. Acanthosis Nigricans.
NGAN DermNet, v. (2004). Acanthosis Nigricans.
Barwell, j. Healthline (2017). Acanthosis Nigricans.
Phillips, et al. Healthline (2016). Laser Therapy.
Roth, e. Healthline (2016). Acne Treatment: Types, Side Effects, and More.
WebMD (2017). Acanthosis Nigricans.