Get to Know More About The Ins and Outs Of The Disease Diabetes Insipidus


Healthy-best.blogspot.com- Diabetes insipidus is a condition that is quite rare, with the symptoms always feel thirsty and at the same time often throw away small amounts of water. If very severe, the sufferer can excrete as much as 20 liters of urine in a day.


Diabetes insipidus is different with its own diabetes mellitus. Diabetes mellitus is a disease characterized by long-term blood sugar levels above normal. Diabetes insipidus, on the other side, is not associated with the levels of sugar in the blood.

Causes Of Diabetes Insipidus
The occurrence of diabetes insipidus due to disruptions in hormone antidiuretic (antidiuretic hormone/ADH) which regulates the amount of fluid in the body. This hormone has produced the hypothalamus, i.e. Special tissue around the brain. These hormones are stored by the pituitary gland once produced by the hypothalamus.

The pituitary gland will secrete hormones antidiuretic this time the water content in the body is too low. ' Antidiuretic ' means ' opposite of diuresis in nature '. ' Production ' means Diuresis urine. Hormones antidiuretic this helps retain water in the body by reducing the amount of fluid is wasted through the kidneys in the form of urine.

That led to the occurrence of diabetes insipidus is an antidiuretic hormone production decreases or when the kidneys no longer respond as usual against the hormone antidiuretic. As a result, the kidneys secrete too much fluid and could not produce a concentrated urine. 

People who experience this condition will always feel thirsty and drinking more fluids trying to offset the large number because it was missing.


Diabetes insipidus itself is divided into two main types, namely:

• Cranial Diabetes insipidus. This type of diabetes insipidus is most common. Due to the body doesn't have enough hormones antidiuretic of the hypothalamus. This condition can be caused by damage to the hypothalamus or the pituitary gland. The damage occurred can be caused by the occurrence of infections, surgery, brain injury, or brain tumor.

• Diabetes insipidus nephrogenic. This type of diabetes insipidus occurs when the body has enough antidiuretic to hormone regulates urine production, but kidney organ not responding to it. This condition may be caused by damage to the kidney organ function or as a condition of offspring. Some of the drugs that are used to address mental illness, such as lithium, can also cause this type of diabetes insipidus.

If you are experiencing symptoms of diabetes insipidus, as always feel thirsty and urinate in excess than usual, you should soon find the doctor. Perhaps you are experiencing is not diabetes insipidus, but it would be better to find out the cause.

Adult pee as much as 4-7 times in a day, while young children do it up to 10 times a day. This is because of children's bladder much smaller. The doctor will do some tests to find out the exact cause and diagnosis against conditions experienced.

Treatment Of Diabetes Insipidus
On cranial diabetes insipidus, treatment may not be necessary in the case of the light. To offset the amount of wasted fluid, you need to consume more water. There are drugs that Act to mimic the role of the antidiuretic hormone called desmopressin. If necessary, you can consume these drugs.

Whereas in diabetes insipidus nephrogenic, a drug that is used to sort it out is a thiazide diuretic. This function decreases the amount of medication of urine produced by the kidney organs.

Complications Of Diabetes Insipidus

The low amount of water or fluid in the body is called dehydration. This is one of the complications caused by diabetes insipidus. If the dehydration happens light enough, you could be drinking oral rehydration therapy to overcome it. But handling in the hospital will be necessary if dehydration is experienced quite severe.


Reference : 
Kalra, S. et al. (2016). Diabetes Insipidus: The Other Diabetes. Indian Journal of Endocrinology and Metabolism, 20(1), pp. 9-21 

Saifan, C. et al. (2013). Diabetes Insipidus: A Challenging Diagnosis with New Drug Therapies. ISRN Nephrology, 10.5402/2013/797620 
Hormone Health (2018). Diabetes Insipidus. 
NHS Choices UK (2016). Health A-Z. Diabetes Insipidus. 
Mayo Clinic (2017). Diseases and Conditions. Diabetes Insipidus. 
Tidy, C. Patient (2015). Diabetes Insipidus.